News
PD-value MabDesign
We are happy to announce that PD-value has officially become a member of MabDesigntheFrench biotherapy industry association. This partnership signifies our unwaveringcommitment to the region and our dedication to fostering growth and collaboration withinour industry....
Season’s Greetings
It is the Holiday Season with festivities and celebrations in many cultures all around the world. No wonder why it is such a special time of the year. It is also the time to reflect on the past year and our experiences. It has been a year with many challenges around...
New Trends and Developments in Systems Biology
If you are following me on LinkedIn, you might have seen my journeys for attending Systems Biology conferences. After such a long period of limited interaction, I felt like reconnecting and catching up with the scientific community was what I needed. And I was in for...
Project Optimus – Dose Optimization and Dose Selection in Oncology
In my last blog, I wrote that I will, specifically, focus on dosing in two blogs, and this one will finalize our mini-series, if you will, on dosing, at least for now. The first post focused more on the technical aspect of the topic, whereas now we will talk about the...
Improving Dose Selection Paradigm in Oncology Drugs through Systems Biology Approaches
We continue to explore the opportunities opening up with the systems approaches in drug development in our blog series. The next two blogs will be specifically dedicated to dosing as it is a crucial aspect of drug development, and recently we have seen some...
From Nice to Have to Best Practice: How the FDA’s focus on Systems Approaches has been increasing
In 2017, the FDA designed the Model Informed Drug Development (MIDD)1 Program to have a platform where the FDA and drug developers can discuss model-based approaches in drug and medical products development. In addition, the program aims to identify the best MIDD...
Systems Pharmacology: What happens when you apply Systems Biology Principles to the field of Pharmacology?
Systems Pharmacology or Quantitative Systems Pharmacology (QSP) is the field where systems biology approaches are explicitly applied to pharmacology. It is, in a way, an intersection between pharmacometrics and systems biology. The aim is to understand how a ‘system’...
Season’s Greetings
The Holiday Season is upon us yet another year under exceptional circumstances. Nonetheless, when we reflect on the past year, we see many positives, learning moments and incredible progress within PD-value and in the world. We would like to say a heartfelt and warm...
PD-value joins MESI-STRAT team to expand the impact of in-silico breast cancer MESIModels in drug development
Utrecht and Innsbruck; December 2021 – PD-value, a leading translational pharmacometrics service company, joined MESI-STRAT, a project funded by European Union's H2020 research and innovation programme. MESI-STRAT aims to develop metabolic and signaling pathway models...
Systems Biology – Understanding and Utilizing Systems Approach in Drug Development
In this blog, we will discuss the foundations of systems biology and practical ways to use this approach in drug development. Let's start basic with some definitions. Systems Biology is an exciting and emerging field that combines mathematical and computational...
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