News
Improving Dose Selection Paradigm in Oncology Drugs through Systems Biology Approaches
We continue to explore the opportunities opening up with the systems approaches in drug development in our blog series. The next two blogs will be specifically dedicated to dosing as it is a crucial aspect of drug development, and recently we have seen some...
From Nice to Have to Best Practice: How the FDA’s focus on Systems Approaches has been increasing
In 2017, the FDA designed the Model Informed Drug Development (MIDD)1 Program to have a platform where the FDA and drug developers can discuss model-based approaches in drug and medical products development. In addition, the program aims to identify the best MIDD...
Systems Pharmacology: What happens when you apply Systems Biology Principles to the field of Pharmacology?
Systems Pharmacology or Quantitative Systems Pharmacology (QSP) is the field where systems biology approaches are explicitly applied to pharmacology. It is, in a way, an intersection between pharmacometrics and systems biology. The aim is to understand how a ‘system’...
Season’s Greetings
The Holiday Season is upon us yet another year under exceptional circumstances. Nonetheless, when we reflect on the past year, we see many positives, learning moments and incredible progress within PD-value and in the world. We would like to say a heartfelt and warm...
PD-value joins MESI-STRAT team to expand the impact of in-silico breast cancer MESIModels in drug development
Utrecht and Innsbruck; December 2021 – PD-value, a leading translational pharmacometrics service company, joined MESI-STRAT, a project funded by European Union's H2020 research and innovation programme. MESI-STRAT aims to develop metabolic and signaling pathway models...
Systems Biology – Understanding and Utilizing Systems Approach in Drug Development
In this blog, we will discuss the foundations of systems biology and practical ways to use this approach in drug development. Let's start basic with some definitions. Systems Biology is an exciting and emerging field that combines mathematical and computational...
Introducing the MoreChi WC Kempo2019 team
The team of MoreChi is a group of excellent sportsmen. One of them, Michiel van Rijn, actually is reigning World Champion Kempo, as he has won the 2018 semi-contact series for the middle weight class. In 2019, two adults will compete in both Fighting and Traditional...
Sponsoring a martial arts tournament team
PD-value is a proud sponsor of the More Chi Martial Arts team for their participation in the World Championship Kempo 2019 in Spain. Martial arts is about improving yourself. That is in a nutshell the link between a pharmacometric company and a martial arts team. The...
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